Configure Infinite Talk and Wan 2.1 models in ComfyUI

ComfyUI Try it →Watch full video →Olares · May 2026

Demo summary

The user demonstrates loading the Infinite Talk model alongside the Wan 2.1 I2V 14B model within ComfyUI, including enabling block swap and torch compile for VRAM optimization.

Step-by-step

Install the One Video Wrapper plugin via the ComfyUI manager
Load the Infinite Talk single model
Load the Wan 2.1 I2V 14B 480P Q6K model
Enable block swap settings to reduce VRAM usage
Enable torch compile settings to speed up the process
Set the clip vision model to clip vision H
Set the VAE to Wan 2.1 VAE

Watch out for

Requires the One Video Wrapper plugin to be installed through the manager as it uses non-native nodes

Tips

Enable block swap and torch compile to optimize performance and VRAM usage

All demos from “Audio-Driven Lip Sync with Infinite Talk | ComfyUI Tutorial S04 P07”

0:510:36Configure Infinite Talk and Wan 2.1 models in ComfyUICurrentThe user demonstrates loading the Infinite Talk model alongside the Wan 2.1 I2V 14B model within ComfyUI, including enabling block swap and torch compile for VRAM optimization.ComfyUI· AI Animation Generator
1:270:23Process audio and images for lip syncThe demonstration shows uploading a character image and using Wav2Vec nodes to extract alignment data from an audio file to generate lip movement instructions.ComfyUI· AI Lip Sync Generator
1:551:13Configure sampling and window settings for long video generationThe user walks through the Wan Video Wrapper sampling node, explaining how to set frame window size, motion frame overlap, and start steps for consistent video generation.ComfyUI· AI Animation Generator
3:080:30Review Infinite Talk lip sync outputThe video shows the final rendered output where a character's lip movements are precisely synced to the input audio, followed by natural movement back to the original pose.ComfyUI· AI Lip Sync Generator
Watch “Audio-Driven Lip Sync with Infinite Talk | ComfyUI Tutorial S04 P07” →

AI Animation Generator

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